Abstract Acute localized exanthematous pustulosis is a localized variant of acute generalized exanthematous pustulosis, which is characterized by the eruption of multiple scattered pustules following drug administration. A 72-year-old woman presented with multiple erythematous pustules on her face, which had appeared two days after using cefoperazone and sodium sulbactam. Histopathological findings showed subcorneal pustules and mixed inflammatory cell infiltration in the dermis. The pustules resolved within about two weeks after the patient discontinued the antibiotics. This report discusses the case of a woman with a cutaneous drug reaction consistent with acute localized exanthematous pustulosis that occurred after cefoperazone and sodium sulbactam were administered.

Abstract Onychogryphosis is an acquired nail plate change. It often affects the toenail and is characterized by an opaque, yellow-brownish nail plate that is distorted, grossly thickened, elongated, and partly curved resembling a ram's horn. Tuberous sclerosis complex is a multisystem disorder associated with high rates of mental retardation, autism, cognitive impairment, behavioral problems, or seizures. Nail disease can also be associated, which is a concern to patients due to pain and nail distortion. We reported a typical tuberous sclerosis complex patient with distinctive clinical features of a ram's horn nails, which presented a great challenge to surgical treatment and nail restoration.

Este trabalho se refere a um estudo de caso da teoria de elasticidade para entender sistemas agrícolas na província de Luancheng na planície do norte da China. Foi construído um modelo de sistema dinâmico acoplado a subsistemas agrícolas sociais, econômicos e ecológicos para a província de Luancheng com um intervalo de tempo de um mês. O modelo inclui cinco componentes principais: recursos hídricos, rentabilidade, irrigação, produção agrícola e área. O lençol freático simulado, a área e a produção de trigo, a área e produção de milho e a transferência de mão de obra refletiram a tendência geral dos resultados observados com coeficientes de determinação maiores que 0.88. A elasticidade dos sistemas agrícolas, indicada pela rentabilidade e segurança alimentar, foi explorada para a província de Luancheng, que mostrou que inicialmente os investimentos em agricultura tiveram sua elasticidade aumentada rapidamente. Entretanto, com a degradação dos recursos e o aumento do investimento agrícola, o custo da produção agrícola tornou-se muito alto para obtenção de lucro. O aumento de população aumenta o risco de segurança alimentar. Como resultado, a elasticidade dos sistemas agrícolas decresceu gradualmente. A província de Luancheng encontra-se agora na fase conservativa do ciclo de adaptação. Ajustes parciais deveriam ser implementados para impulsionar sua elasticidade e promover o desenvolvimento contínuo dos sistemas agrícolas.

This paper presents a case study of resilience theory to understand agricultural systems in the Luancheng County of the North China Plain. A dynanic system model coupled with social, economic and ecological subsystems of agriculture for the Luancheng County was constructed with a time step of one month. The model includes five main components, water resources, profitability, irrigation, crop yield and area. The simulated groundwater table, wheat area and yield, maize area and yield, and rural labor transfer reflected the general trend of the observed data, with calculated determination coefficients higher than 0.88. Resilience of agricultural systems, as indicated by agricultural profitability and food security, were explored for the Luancheng County. Initially, investments in agriculture increased its resilience rapidly. However, with the degradation of resources and the increases in agricultural investment, the cost of agricultural production became too high to gain profit. The rise in population increases the risk of food security. As a result, the resilience of agricultural systems decreased gradually. The Luancheng County is now in the conservation phase of the adaptive cycle. Partial adjustments should be introduced to enhance its resilience and promote the continuing development of the agricultural systems.